Make Blind People to See Again.

Speaker: 엄경식 교수(부산대)

Date & Time: 2019년 10월 2일(수), 17:00

Where: D-122호

Abstract

Retinitis pigmentosa, age-related macular degeneration, and Stargardt disease are the most common incurable eye diseases associated with outer retinal degeneration leading to blindness. Among the various current trials to cure those diseases including optogenetic stimulation and stem cell therapy, only electrical retinal prosthetics has validated clinical promise. Since most retinal ganglion cells (RGCs) in those diseases remain intact, the cells can convey visual signals to the brain when properly stimulated as in the electrical retinal prosthetics. Yet, the electrical prosthetics still suffers from fundamental limitations such as the invasive nature of the device and both the limited number and fixed location of stimulation sites. Here, this study establishes the feasibility of novel, minimally-invasive, high-resolution retinal prosthetics in animal models, based on an emerging neuromodulation approach, nanoparticle-enhanced near-infrared neural stimulation. When a neuron is attached with gold nanorods (AuNRs), near-infrared (NIR) light illumination with a wavelength matching to the nanorod’s resonant wavelength was shown to activate the neuron via photothermal effects. In this talk, novel optical tool development and its theoretical background will be presented. Ex vivo and in vivo validation of minimally-invasive retinal prosthesis will be demonstrated.

Biography

[학력]

Ph.D Electrical and Computer Engineering, Seoul National University, Seoul, Korea [2016]

M.S. Electrical and Computer Engineering, Seoul National University, Seoul, Korea [2012]

B.S. Electrical Engineering, KAIST, Deajeon, Korea [2010]

[경력]

Assistant Professor, Department of Electronics Engineering, Pusan National University [2019. 9 – present]

Post-doctoral fellow, School of Engineering, Brown University [2016. 11 – 2019. 8]

초청자 : 융합과학부 나노융합전공 송윤규 교수(songyk@snu.ac.kr)

2019-09-30|