[나융]Nanobiosensor for non-destructive characterizations of stem cell behaviors

Speaker: Assistant Professor, Tae-Hyung Kim (School of Integrative Engineering, Chung-Ang University)

Date & Time: 2018년 3월 14일 (수) 17:00

Where: 융대원 D-122호

Abstract

Stem cells are promising sources in the field of regenerative medicine due to their innate ability to produce a number of different cells. To exploit the potential of stem cells, the types of cells generated from various stem cell sources need to be precisely identified. Here, we report a new type of nanobiosensor that is effective to monitor stem cell differentiation into specific lineages, as well as to characterize stem cell pluripotency in non-destructive manner. By using the new nanohybrid platforms, we could precisely analyze the changes of several stem cell characteristics: i) the multipotency of mouse neural stem cells, ii) the differentiation of human neural stem cells into dopaminergic neurons and iii) the osteogenesis and adipogenesis of human adipose-derived mesenchymal stem cells. Furthermore, we have shown that the nanohybrid platform also could be utilized to detect undifferentiated human embryonic stem cells (hESCs) in a quantitative manner. Therefore, we can conclude that the developed cell-based nanobiosensor could be highly useful for in situ monitoring of stem cell behaviors, which will be eventually promising for cell-based regenerative medicine.

Biography

학력

Ph.D Chemical and Biomolecular Engineering, Sogang University, Seoul, Korea [2013]

B.S. Chemical Engineering, Sogang University, Seoul, Korea [2008]

경력

Assistant Professor, School of Integrative Engineering, Chung-Ang University, Seoul, Korea [2015.9 – present]

Post-doctoral fellow, Rutgers, The State University of New Jersey-New Brunswick, U.S.A [2013.3 – 2015. 8]

초청자 : 융합과학부 나노융합전공 이강원 교수(연락처 :031-888-9145, kangwonlee@snu.ac.kr )

2018-03-13|